A field experiment was conducted at College Farm, Gwalior in M. P. during the rainy (kharif) seasons of 2013 and 2014 to study the seed yield and nutrient uptake studies on clusterbean as influenced by mulching practices, varieties and nutrient management. Results revealed that plastic mulch significantlyincreased the seed and stover yields as well as N, P and K uptake over the weed biomass mulch and no mulch. Variety HG-563 recorded significantly higher seed, stover yield, N, P and K uptake by seed, stover and total uptake as compared to RGC-1055. Among the fertility levels, application of 75% RDF+VC 5 t/ha resulted in significantly higher seed, stover yield, N, P and K uptake by seed, stover and total uptakeover all the remaining fertility levels. After harvest of crop, the available N, P and K in the soil increased in weed biomass mulch with RGC-1055 under 50% recommended dose of fertilizer+vermicompost 5 t/ha as compared to other treatments during both the years.