Therefore, a simple, completely factorial randomized pot experiment was conducted during 2018 at pot culture yard, Department of Soil Science and Agricultural Chemistry, Annamalai University to evaluate the effect of organic and inorganic sources and levels of boron on growth and yield, quality attributes and uptake by cotton under salt stress condition. The experiment was conducted with four levels of boron (0, 0.5, 1.0 and 1.5 mg//kg of soil) through three sources viz., borox, solubar and magnesium borohumate complexes. The cotton variety LRA5166 was used as test variety. The results revealed that application of 1.5 kg of B through magnesium borohumate (MBH) complex recorded the higher plant height (124.6 cm), leaf area index (4.82), DMP (216 g/pot), yield components like number of bolls per plant (18.20), and mean boll weight (3.92) of cotton in saline sodic soil. Furthermore, higher seed cotton yield (93.51 g/pot), seed yield (54.72 g/pot) and lint yield (33.53 72 g/pot) were also recorded. This was on par with application of 1.0 kg of B through magnesium borohumate and recorded the plant height (122.81 cm), leaf area index (4.7), DMP (213 g/pot), yield components like number of bolls per plant (17.4), and mean boll weight (3.83 g), seed cotton yield (92.71 g/pot), seed yield (54.1 g/pot) and lint yield (32.96 g/pot) and followed by S2L4 (1.5 kg of B through solubar). The conclusion made from this study is the application of boron through 1.0 kg of B through magnesium borohumate will sustainably increase the cotton yield in saline sodic soil.