An experiment was conducted to study the integrated plant nutrient management in guava (Psidium guajava L.) cv. Allahabad Safeda in the Experimental Farm and Laboratory, Department of Horticulture, Assam Agricultural University, Jorhat during 2015–17. A total of nine treatments including a control with three replications and two seasons were laid out in a randomized block design. During the period of investigation, the treatments showed varied response to soil parameters. Studies revealed that soil N, P, K, MBC and various soil enzymes such as dehydrogenase, phosphomonoesterase, fluorescein di-acetate hydrolase, bacterial and fungal population were found to be the highest in T8 (Half of RDF+10 kg vermicompost+100 g microbial consortium+0.4% ZnSO4+0.4% boric acid).