A field experiment was conducted during kharif 2015 at Agricultural Research Farm, TCA, Dholi, a campas of Rajendra Agricultural University, Pusa, Bihar to study the effect of different doses of pre-and post-emergence herbicides in tank mixture on complex weed flora, yield and yield components of kharif maize. Weed infestation caused 37.4% reduction in grain yield of maize. Maximum values of yield and yield attributing characters were recorded under weed free situation (hand weeding twice at 20 and 40 DAS) (T2) being statistically at par with atrazine @ 1.5 kg/ha pre-emergence fb halosulfuron @ 60 g/ha at 25 DAS post-emergence (T7). However, the maximum weed control efficiency and minimum weed index were obtained with hand weeding twice at 20 and 40 DAS. Among the different herbicidal treatments, application of atrazine @ 1.5 kg/ha as PE fb halosulfuran @ 60 g/ha was most effective against complex weed flora in kharif maize.