Distillery sentwash is effective organic liquid manure derived from molasses based distillery industries after biomethanation process. A field experiment was conducted during 2009 in Research and Development Farm of M/s. Bannari Amman Sugars Distillery Division Ltd., Erode to find out the concentration dosage of spentwash with inorganic fertilizers to obtain the maximum growth, quality and yield of maize (COH (M) 5). From the experiment, quality, physiological, biochemical and nutrient parameters were estimated. Growth, yield attributes and yield were recorded. The results revealed that application of spentwash @ 100 m3/ha+recommended dose of N, P and K recorded the higher grain and cob yield of 5815 and 6513 kg/ha, respectively, which was on par with spentwash @ 100 m3/ha+recommended dose of N and P over recommended dose of fertilizers. The utilization of spentwash increased the growth parameters thus enhancing the yield besides paving an ecofriendly approach for the disposal of the effluent.