Today, the need for grain is increasing every day due to the growing human population on the planet. At the same time, global climate change has a negative impact on grain production. The main grain-producing regions of Kazakhstan are also currently facing water shortages and soil fertility problems. Therefore, an experiment was conducted during 2019 and 2020 at LLC «South-west Research Institute of Livestock and Crop Production» (South Kazakhstan) to determine the actual dates, and the number of irrigation schemes, irrigation and orastitelnye standards in the different phases of growth and development of soybean plants under conditions dry and hot climate of the south part of Kazakhstan. Soybean crops under irrigation conditions in the south of Kazakhstan. Objects of research: Sowing of soybeans in conditions of irrigation in the south of Kazakhstan. Zoned soybean variety “Lastochka”. In the conditions of the hot and dry climate of the south of Kazakhstan, the main limiting factor of the yield of soybean plants is the lack of moisture and nutrition elements. According to the research results, it was found that when maintaining optimal soybean irrigation regimes in combination with mineral fertilizer norms, taking into account the needs of plants, they ensure consistently high yields of soybean grain at the level of 30 c/ha. In the conditions of the south of Kazakhstan, optimization of the soybean irrigation regime and regulation of the nutrition regime are an effective method for obtaining consistently high grain yields from the irrigated territory.