The present investigation was undertaken during the spring crop (January to June 2019) at greenhouse in the Don Duong cultivation farm, Lam Dong province, Vietnam to evaluate the effect of drip irrigation combined with agricultural mulches on RITA tomato. The study is conducted applying agricultural mulches in greenhouse (AMG) with irrigation water level (IWL) 80% of actual evapotranspiration (ETa) and no agricultural mulches outside greenhouse (AMO) with IWL 100% of ETa to plant tomatoes cuttings. Based on the findings, highest tomato yield obtained for AMG was 81.6 ton/ha while for AMO was 67.8 ton/ha. The highest income for AMO case was US$ 4559/ha while for AMG case achieved up to US$ 7658/ha. The study, therefore, demonstrated the effect of the drip irrigation combined with agricultural mulches compared to the agricultural un-mulches case.