Mangosteen a delicious fruit with high economic value has a short shelf-life which is a biggest obstacle in its wide scale consumption and transportation. Edible biopolymers coating can provide a replacement as well as fortify natural layers to prevent moisture loss, while selectively allowing for controlled gas exchange involved in respiration process. To further evaluate, a study was conducted during 2020 at Soc Trang Nanotech laboratory, Soc Trang province, Vietnam to examine the possibility of chitosan-silver nanoparticle coating to preserve mangosteen fruit for 35 days. Our results revealed that chitosan 0.4%: AgNO3 1 mM showed significant time delay of ripening of the fruits by retaining the weight loss, firmness, total soluble solid, ascorbic acid, total phenolic content. By the chitosan-silver nanoparticle coating, shelf life of mangosteen fruit would be effectively extended for 35 days.