Field experiment was conducted during the growing season of 2017–18 in Basra governorate to study the effect of three tillage depth “TD” (30, 40 and 50 cm), and spraying with three activated yeast extract “AYE” concentrations (zero, 4 and 8 g/l) on growth and yield of broad bean (Vicia faba L.) var. loz de onito. The experiment was carried out in a split-plot arranged with randomized complete block design with three replicates. The results showed that TD of 50 cm led to an increase in plant height, number of branches in plant, also led to a significant increase in the number of pods and number of seeds in pod by 26 and 21%, respectively, compared to the TD of 30 cm, also held green pods yield of 327.2 g/plant at TD of 30 cm increased to 547.5 g/plant at 50 cm depth. Spraying AYE at 8 g/l resulted in a significant increase for all traits that have been studied, among these traits number of pods/plant and number of seeds/pod by 16 and 22%, respectively, compared to control. The interaction gave a significant increase for plant height and green pods yield per plant, so the TD at 50 cm and 8 g/l AYE gave the highest values.