The objective of this study was to determine the effects of different soil salinity levels on the agronimic traits and yield of four newly introduced salt-tolerant rice cultivars in the Thua Thien Hue province, Central Vietnam. Three field experiments were conducted in 2018 summer-autumn crop season at three locations with different soil salinity levels of EC 4.1, 6.4 and 9.0 dS/m. Yield per plant and some agronomic traits including of plant height, panicle length and number of filled grains per panicle were measured. The cultivars of MNR3, OM5629 and OM2395 showed significantly higher yield per plant than that of the commonly used cultivar KD. As soil salinity increased from 4.1 to 6.4 dS/m, 6.4 to 9.0 dS/m, and 4.1 to 9.0 dS/m, yield per plant decreased 18.2, 16.0 and 31.3%, respectively. Therefore, it could be concluded that these cultivars were suitable for cultivation on saline soils in the summer Vautumn crop season at soil with EC T6.4 dS/m in Central Vietnam.