An experiment was conducted at AICRP on Weed Management Farm, BACA, AAU, Anand, Gujarat with a view to manage the diverse weed flora in garlic (Allium sativum L.) through eco-friendly approach. The experiment was laid out in split plot design (SPT) with three replications. Results indicated that application of oxyfluorfen 240 g/ha PE fb HW at 60 DAP and tank mix application of pendimethalin 500 g/ha EPoE + oxyfluorfen 120 g/ha EPoE along with paddy straw mulch 5.0 t/ha applied after planting effectively reduced the density and dry weight of weeds with higher weed control efficiency in garlic. The said treatments also recorded higher 100-clove weight (g), bulb weight (g/bulb), number of cloves/bulb, bulb yield of garlic (t/ha), the highest net returns (Rs. 273760 and Rs. 230152/ha) and B: C ratio (3.79 and 3.44.), respectively.