An experiment was conducted for two years at College Farm, College of Agriculture, Rajendranagar, Hyderabad during kharif 2009 and 2010 to study the effect of organic sources and fertilizer levels on nutrient uptake by hybrid rice at different stages of crop growth. The experiment was laid out in split plot design with three replications. The treatments included organic sources (No organic manuring–control, subabul incorporation @ 5 t/ha, rice straw incorporation @ 2.5 t/ha) as main plot treatments and fertilizer levels comprising N: K2O kg/ha (150: 75, 175: 50, 175: 25, 200: 50, 200: 25, 225: 0) as sub-plot treatments. The results revealed that among the organic sources, subabul incorporation @ 5 t/ha recorded the highest nutrient uptake at all stages of crop growth, while 200: 50 N: K2O kg/ha was the best fertilizer level. The interaction effect between organic sources and fertilizer levels was found significant. Subabul incorporation @ 5 t/ha coupled with 200: 50 N: K2O kg/ha recorded the highest nitrogen and potassium uptake and remained on par with subabul incorporation @ 5 t/ha coupled with 200: 25 N: K2O kg/ha.