Strychnos nux-vomica has already proved for its insecticidal activity. The present study was conducted with an attempt to check the insecticidal activity against mango leafhopper. Three different solvents were used for preparation of extracts of Strychnos nux-vomica viz., petroleum ether, ethanol and ethyl alcohol. Insecticidal activity shows significant results i.e. p<0.05. Least Significant Difference (LSD) showed statistically significant difference in mortality for petroleum ether and ethanol & petroleum ether and ethyl acetate. Strychnos nux-vomica has proven potential for its effectiveness against Idioscopus clypealis Leth. It will be beneficial for the agricultural sector.